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Research Associate III - Jiang Lab - Lung Institute

Los Angeles, California

Overview

Cedars-Sinai is a hub for biomedical research and a training center for future physicians and other healthcare professionals. By joining us in an academic role, you’ll be a part of formulating future ideas for discovery and then translating those discoveries into cures for the benefit and health of the Los Angeles community.

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Success Profile

What makes a successful Research Associate III - Jiang Lab - Lung Institute at Cedars-Sinai? Check out the traits we’re looking for and see if you have the right mix.

  • Analytical
  • Organized
  • Deadline-oriented
  • Adaptable
  • Results-driven
  • Problem-solver

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Culture

Discovery is central to Cedars-Sinai’s mission. Our laboratories and clinics generate ideas, therapies, devices, and systems that contribute to biomedical progress around the world. Cedars-Sinai’s investigators push the frontiers of biomedicine with studies in cardiac care, cancer, digestive health, the neurosciences, women’s health, and more. Cedars-Sinai’s robust academic enterprise shapes the experts who will help redefine medicine for the next generation.

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Responsibilities

Requisition # HRC0869818

Are you looking to contribute to groundbreaking research? If your answer is 'yes', then we invite you to apply to this rewarding opportunity!

Cedars-Sinai offers scientists unparalleled access to cutting-edge technologies, facilities, and resources for conducting research related to an impressive range of diseases and disorders, from cancer, cardiology, and digestive diseases, to genetics, genomics, neurosciences, and women's health. You can continue your career journey with us!

Principal Investigator, Dianhua Jiang, PhD, is seeking for a self-motivated Research Associate III to join his laboratory!

The Jiang Laboratory focuses on cellular and molecular mechanisms of lung inflammation and fibrosis, the role of lung stem cells in pulmonary fibrosis, and the role of host defense in lung inflammation and fibrosis. The Jiang Laboratory is affiliated with the Pulmonary Division in the Department of Medicine and Women's Guild Lung Institute. To learn more about this laboratory, please visit the Jiang Research Lab website

As a Research Associate III and under general guidance, you will work closely with Principal Investigator, providing technical and/or administrative support in large or multi-project-oriented labs. In this role, you may be requested by the Principal Investigator to take on specific supervisory activities, and provide administrative leadership, and/or technical expertise. You may develop hypothesis and assist in planning steps for the investigative process. You will review and remain current on literature as it relates to clinical/research study. This position also coordinates all lab and/or clinical activities, including but not limited to, budgetary/financial compliance, preparation of grant proposals, and creating independent presentations. This role is not responsible for generating grant funds.

Primary Duties and Responsibilities:

  • Provides miscellaneous clinical/research support (ad hoc data analysis, hypothesis development, programming, troubleshooting, etc.).  
  • Organizes clinical/research trials in conjunction with the Principal Investigator and sponsor and/or funding source.
  • Monitors and ensures compliance with safety standards and procedures.  
  • Analyzes data and prepares scientific findings for publication as author or co-author.  
  • May make independent presentations.  
  • May provide system administration and maintenance for the local workstation network.  
  • Leads and trains Research Lab Assistants, Research Fellow, lower level Research Associates, and other related support staff and may be requested by PI to take on specific supervisory activities.
  • Orients new Research Fellows and/or Research Scientists to day-to-day lab operations and procedures.  

Department-Specific Duties and Responsibilities:

This role will lead the development of novel in vitro assays. The assays and methods include transformation of primary cells from human explants, phenotypic validation, clonal expansion, establishment of knock-in of allele-specific marker genes, 3D organoid culture, phenotypic screening, as well as small molecule screening. These assays and methods may be used to investigate the pathogenic epithelial cells in fibrotic lung diseases.

The candidates are expected to carry out the projects independently with minimal supervision, including designing experiments, formulating new ideas related to the projects, executing experiments proficiently and timely, and analyzing data professionally. The scientists are expected to supervise others including assay development, problem solving, interpreting results and planning follow-up experiments.

 

Education: 

  • Bachelor's degree in a Science related field, required. 
  • Master's degree or Doctorate degree in Cell Biology or a related field, highly preferred.

Experience: 

  • 3 years of experience in research laboratory, required. 
  • Has technical skills and expertise in an area of study including, but not limited to, Molecular/Cellular Biology, Neuroscience, engineering, or mass spectometry.  
  • Experience in cutting-edge histology/imaging techniques including quantitative bright-field and fluorescence microscopy, confocal microscopy, and electron microscopy is required.  
  • Strong computer skills (MS Word, MS Excel, MS Access, PowerPoint).  
  • Strong analytical and problem-solving skills.
  • Excellent organization skills and very detail-oriented.
  • Ability to learn new tasks quickly and be self-motivated.
  • Works well independently with minimal supervision and with others.
  • Ability to multi-task.  
  • Strong interpersonal skills for interaction with peers, patients, physicians, and other customers of the medical center.  
  • Thorough technical and theoretical understanding of PI’s research objectives.  
  • Mastery of complex or unusual technical procedures and protocols.  
  • 5-year extensive hands-on research experience in primary epithelial cell culture, progenitor organoid culture, immortalization, and clonality are highly preferred.
  • Experience and knowledge of CRISPR knock-in and high content phenotypic screening are preferred.

 

Physical Demands: 

Able to perform moderate lifting.  Able to sit, stand and walk for prolonged periods of time.  Able to read papers and online documents.  Able to operate standard office equipment.  Able to exercise physical ability and perspective acuity to satisfactorily perform essential job functions.

  • Working Title: Research Associate III - Jiang Lab - Lung Institute
  • Department: Home Dept - Pulmonary
  • Business Entity: Academic / Research
  • City: Los Angeles
  • Job Category: Academic/Research
  • Job Specialty: Research Studies/Clinical Trials
  • Position Type: Full-time
  • Shift Length: 8 hour shift
  • Shift Type: Day

Cedars-Sinai is an EEO employer. Cedars-Sinai does not unlawfully discriminate on the basis of the race, religion, color, national origin, citizenship, ancestry, physical or mental disability, legally protected medical condition (cancer-related or genetic characteristics or any genetic information), marital status, sex, gender, sexual orientation, gender identity, gender expression, pregnancy, age (40 or older), military and/or veteran status or any other basis protected by federal or state law. If you need a reasonable accommodation for any part of the employment process, please contact us by email at Applicant_Accommodation@cshs.org and let us know the nature of your request and your contact information. Requests for accommodation will be considered on a case-by-case basis. Please note that only inquiries concerning a request for reasonable accommodation will be responded to from this email address.

Cedars-Sinai will consider for employment qualified applicants with criminal histories, in accordance with the Los Angeles Fair Chance Initiative for Hiring.

At Cedars-Sinai, we are dedicated to the safety, health and wellbeing of our patients and employees. This includes protecting our patients from communicable diseases, such as influenza (flu) and COVID-19. For this reason, we require that all new employees receive a flu vaccine based on the seasonal availability of flu vaccine (typically during September through April each year) as a condition of employment, and annually thereafter as a condition of continued employment, subject to medical exemption or religious accommodation. For the same reason, you may also be required to receive other vaccines such as COVID-19 as a condition of employment. Cedars-Sinai reserves the right to make modifications to its required list of vaccines as required by law and/or policy.

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Rewards

Discover all the ways Cedars-Sinai appreciates your efforts.

  • Healthcare

  • 401(K)/Retirement Plans

  • Continuing Education

  • Relocation Reimbursement

  • Professional Development

  • Work/life Balance

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