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Postdoctoral Scientist - Telomerase - Cancer Institute

Requisition # 19002008 Apply Now

The Theodorescu Lab at Cedars-Sinai in Los Angeles, along with collaborators, has made significant contributions in the areas of telomerase biology. These contributions include finding a high frequency of TERT promoter mutations (Clin Cancer Res. 2014 20(18):4935), the impact of these TERT mutations on TERT expression, and the clinical relevance of these mutations in patients (Science. 2015;347(6225):1006). Further discoveries have been made in TERT regulation (Genes Dev. 2015 29(21):2219). We are seeking a highly motivated individual to further develop this work as well as discover and investigate the role of TERT, its regulators and effectors, in cancer progression and metastasis. In addition, the laboratory has ongoing drug discovery projects directed at key molecules involved in telomerase biology which may interest the individual.

 

This individual would join our exciting cancer research group. The successful candidate will be a driven, creative, team-oriented individual with a passion for helping to discover and move fundamental cancer biologic findings towards a clinical setting. The candidate will have a PhD or MD/PhD degree and background in transcription/gene regulation biology or related field as well as in functional genomics (including CRISPR, shRNA and cDNA library use). A broad based knowledge of signal transduction and biochemistry/chemistry is an important characteristic of the successful applicant. We welcome applications who are completing their PhD as well as individuals seeking additional postdoctoral training. Strong preference will be given to individuals with an outstanding publication record from their prior graduate and/or postgraduate training and/or existing external funding. For more information please visit: https://www.cedars-sinai.edu/Research/Research-Labs/Theodorescu-Lab/

 

Essential Job Duties and Responsibilities:

 

Designs and performs experiments. Keeps detailed experimental records and documentation and analyze the results with the Principal Investigator. 

 

Develops, adapts, and implements new research techniques and protocols.

 

Analyzes, interprets, summarizes and compiles data. 

 

Performs routine and complex laboratory procedures throughout training period.

 

Assists in preparation of grant proposals but is not responsible for generating grant funds.

 

Participates in publications and presentations as author or co-author.

 

Meets with PI on a regular basis to discuss research progress and plans. 

 

May be asked to write small grant proposals or NRSA/T32 applications.

 

Spends about 75% of time on bench research experimentation and 25% of time on writing articles/analyzing data/online research.

Educational Requirements:

Doctorate (PhD or MD/PhD) in molecular biology, or area directly related to field of research specialization.


Experience:

Has the ability to works semi-independently on research projects within an area of specialization. Has thorough technical and theoretical knowledge of research project and the objectives to be accomplished during the one to five (1-5) year post-doctoral appointment. Demonstrates aptitude to perform experimental protocols and procedures, including detailed data collection and analysis.

  • Working Title: Postdoctoral Scientist - Telomerase - Cancer Institute
  • Department: Home Dept - Hem - Onc
  • Business Entity: Academic / Research
  • City: Los Angeles
  • Job Category: Academic / Research
  • Job Specialty: Postdoctoral
  • Position Type: Full-time
  • Shift Length: 8 hour shift
  • Shift Type: Day
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Cedars-Sinai is an EEO employer. Cedars-Sinai does not unlawfully discriminate on the basis of the race, religion, color, national origin, citizenship, ancestry, physical or mental disability, legally protected medical condition (cancer-related or genetic characteristics or any genetic information), marital status, sex, gender, sexual orientation, gender identity, gender expression, pregnancy, age (40 or older), military and/or veteran status or any other basis protected by federal or state law. If you need a reasonable accommodation for any part of the employment process, please contact us by email at Applicant_Accommodation@cshs.org and let us know the nature of your request and your contact information. Requests for accommodation will be considered on a case-by-case basis. Please note that only inquiries concerning a request for reasonable accommodation will be responded to from this email address.

Cedars-Sinai will consider for employment qualified applicants with criminal histories, in accordance with the Los Angeles Fair Chance Initiative for Hiring.

At Cedars-Sinai, we are dedicated to the safety, health and wellbeing of our patients and employees. This includes protecting our patients from communicable diseases, such as influenza (flu). For this reason, we require that all new employees receive a flu vaccine based on the seasonal availability of flu vaccine (typically during September through March each year) as a condition of employment, and annually thereafter as a condition of continued employment.

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Los Angeles, California

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