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Postdoctoral Scientist - Smidt Heart Institute - Department of Cardiology - Fert-Bober Lab

Requisition # 20003505 Apply Now

A postdoctoral position is available at the Fert-Bober’s lab, Cedars Sinai, Smidt Heart Institute. Our successful candidate will investigate molecular mechanisms of cardiovascular development, regeneration and cardiac fibrosis using mass spectrometric-based proteomics methods for the study of proteins and their roles in cellular signaling events. We also develop and apply the technology to the search for post-translational modified proteins, including citrullination. Dysregulated citrullination is a key element that drives the production and maintenance of antibodies to citrullinated proteins, a hallmark in rheumatoid arthritis. The long-term goal is to determine whether citrullinated proteins or antibody to citrullinated proteins can be use as biomarkers for the early detection of many disease, including rheumatoid arthritis, cancer and Alzheimer disease.

 

Working independently but in close consultation with the Principal Investigator and other Research Scientists, you will perform routine and complex laboratory procedures throughout the training period, and may develop, adapt, and implement new research techniques and protocols while analyzing and interpreting data. You will participate in publications and presentations as author or co-author and may assist in the preparation of grant proposals but are not responsible for generating grant funds.

Educational Requirements

  • Ph.D. and/or M.D. required
  • Less than 2 years of postdoctoral experience is strongly preferred

Experience/expertise in the following:

  • A basic understanding of cardiovascular development, regeneration and cardiac fibrosis is required.
  • Skills in isolation and characterization of different cardiac cell types from mouse hearts. 
  • Skills in culture and maintenance of mammalian cell lines.
  • Skills in cardiac tissue histology and proficiency in microscopy.
  • Experience in cell manipulation, flow cytometry and cell sorting, cell tracking, and advanced cell imaging tools.
  • Experience in standard molecular biology techniques (eg. Cloning, qRT-PCR).
  • Computational processing and analysis of genome scale data including RNA-seq, or proteomics is highly desired.
  • Ability to multitask and complete work on time. Ability to contribute and work in a cross-functional, multi-disciplinary team environment.
  • Good verbal and written communication skills in English.
  • Well organized, able to plan work appropriately. 
  • Strong attention to detail. 
  • Strong problem-solving skills.

  • Working Title: Postdoctoral Scientist - Smidt Heart Institute - Department of Cardiology - Fert-Bober Lab
  • Department: Heart Institute Operations
  • Business Entity: Academic / Research
  • City: Los Angeles
  • Job Category: Academic/Research
  • Job Specialty: Postdoctoral
  • Position Type: Full-time
  • Shift Length: 8 hour shift
  • Shift Type: Day
Apply Now

Cedars-Sinai is an EEO employer. Cedars-Sinai does not unlawfully discriminate on the basis of the race, religion, color, national origin, citizenship, ancestry, physical or mental disability, legally protected medical condition (cancer-related or genetic characteristics or any genetic information), marital status, sex, gender, sexual orientation, gender identity, gender expression, pregnancy, age (40 or older), military and/or veteran status or any other basis protected by federal or state law. If you need a reasonable accommodation for any part of the employment process, please contact us by email at Applicant_Accommodation@cshs.org and let us know the nature of your request and your contact information. Requests for accommodation will be considered on a case-by-case basis. Please note that only inquiries concerning a request for reasonable accommodation will be responded to from this email address.

Cedars-Sinai will consider for employment qualified applicants with criminal histories, in accordance with the Los Angeles Fair Chance Initiative for Hiring.

At Cedars-Sinai, we are dedicated to the safety, health and wellbeing of our patients and employees. This includes protecting our patients from communicable diseases, such as influenza (flu). For this reason, we require that all new employees receive a flu vaccine based on the seasonal availability of flu vaccine (typically during September through March each year) as a condition of employment, and annually thereafter as a condition of continued employment.

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Los Angeles, California

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